SPR
- Election Commission of Malaysia
- FN Special Police Rifle
- Mk 12 Special Purpose Rifle
- Pindad
- Pindad SPR
- San Pedro Airport
- Sapphire Rapids
- Saving Private Ryan
- Second Polish Republic
- Self-Publishing Review
- Single particle analysis
- Sistema Público de Radiodifusión del Estado Mexicano
- Society for Psychical Research
- Society for Psychotherapy Research
- Software Productivity Research
- South Persia Rifles
- Specialist registrar
- Spirit AeroSystems
- Strategic Petroleum Reserve (disambiguation)
- Subtree pruning and regrafting
- Suomen Punainen Risti
- Surface plasmon resonance
- São Paulo Railway Company
- Transmission electron microscope