SPB
- Belarus Free Trade Union
- Charlotte Amalie Harbor Seaplane Base
- Government procurement
- IEEE 802.1aq
- S. P. Balasubrahmanyam
- SPB Software
- SPB TV
- Saint Paul's Bay
- Saint Petersburg
- Scappoose Industrial Airpark
- Schynige Platte Railway
- Shepherd's Bush railway station
- Slowly pulsating B star
- Socialist Party of Bangladesh
- Society of the Precious Blood
- South Park Blocks
- Sparisjóðabanki
- Spindle pole body
- Superpressure balloon