SLE (disambiguation)
- CCSDS
- McNary Field
- SUSE Linux Enterprise
- Sara Lee Corporation
- Schramm–Loewner evolution
- Sea level equation
- Seletar Expressway
- Semiconductor luminescence equations
- Separate legal entity
- Shore Line East
- Sierra Leone
- Sierra Leonean leone
- Single loss expectancy
- Sleeper Either Class
- Societas Linguistica Europaea
- Spearhead Land Element
- Sri Lankan English
- St. Louis encephalitis
- Supported leading edge
- Systemic lupus erythematosus