Sodium-dependent phosphate transport protein 2B

Sodium-dependent phosphate transport protein 2B is a protein that in humans is encoded by the SLC34A2 gene.

Clinical significance

Sodium-dependent phosphate transport protein 2b is a tumor-associated antigen.
As of April 2023, upifitamab rilsodotin, an antibody-drug conjugate targeting NaPi2b, is in Phase 3 clinical trials for recurrent platinum-sensitive ovarian cancer.