SIC
- Block cipher modes of operation
- International Financial Reporting Standards
- Landmark detection
- Marco Simoncelli
- S.I.C. (Krizz Kaliko EP)
- SC (disambiguation)
- SIC (magazine)
- SIC Caras
- SIC Ferries
- SIC Insurance Company
- SIC Internacional
- SIC K
- SIC Mulher
- SIC Notícias
- SIC Radical
- SIC TV
- San Isidro Club
- Scottish Independence Convention
- Second-in-command
- Security Insurance Company
- Self-interference cancellation
- Sepang International Circuit
- Sepang Racing Team
- Shetland Islands Council
- Sic
- Sic (album)
- Sic (band)
- Sic, Cluj
- Sick (disambiguation)
- Simplified Instructional Computer
- Sistema Interconectado Central
- Slipknot (album)
- Sociedade Independente de Comunicação
- Southeastern Illinois College
- Standard Industrial Classification
- Successive Interference Cancellation
- Super Imaginative Chogokin
- Swiss Interbank Clearing
- United Kingdom Standard Industrial Classification of Economic Activities