SHC
- Canadian Historical Association
- SHC1
- Sacred Heart Cathedral (disambiguation)
- Sacred Heart Cathedral Preparatory
- Sacred Heart College, Auckland
- Sacred Hearts Club
- Saharsa Junction railway station
- Schreyer Honors College
- Serving His Children
- Shc (shell script compiler)
- Sirohydrochlorin
- Society of the Holy Cross (Korea)
- South Health Campus
- Specific heat capacity
- Spontaneous human combustion
- Spring Hill College
- Src homology 2 domain-containing
- Stanford Humanities Center