SGC
- Earth station
- Grover Cleveland
- League of Legends
- SGC (wine)
- SGC Records
- ScrewAttack
- Secretary-General of the Council of the European Union
- Sega Genesis Collection
- Server-Gated Cryptography
- Soluble guanylate cyclase
- Sonic Gems Collection
- Southern Gospel Choir
- Standard Geographical Classification code (Canada)
- Stargate Command
- Structural Genomics Consortium