SC 295 travels westward from South Pine Street, north of Pacolet, running parallel to railroad tracks until it reaches the city limits of Spartanburg. It continues west, passes next to the airport, and curves north. It then runs concurrently with for about 4,600 ft. and runs next to for about 2.5 miles. Then, it joins up with a frontage road of near the Saxon-Southern Shops-Arcadia line, and ends at the intersection of I-85Bus. and New CutRoad.