SCE
- China SCE Property
- Hong Kong Certificate of Education Examination
- Intelligent Network
- Sami Shamoon College of Engineering
- Saturated calomel electrode
- Saudi Council of Engineers
- Scalable Cluster Environment
- School of Continuing Education
- School of Continuing Education, Hong Kong Baptist University
- Scottish Certificate of Education
- Service Children's Education
- Short-channel effect
- Singapore Combat Engineers
- Sister chromatid exchange
- Societas cooperativa Europaea
- Sony Computer Entertainment
- Sony Interactive Entertainment
- Southern California Edison
- Standard Canadian English
- Starfleet Corps of Engineers
- State College Regional Airport
- Subcutaneous emphysema
- Swedish Cyprus Expedition
- System Center Essentials