Rugulovasine
Rugulovasines are bio-active alkaloids made by Penicillium. Rugulovasine A and B bind strongly to the 5-HT1A, 5-HT2A, and 5-HT2C receptors, but lack meaningful binding affinity towards the Alpha-1 [adrenergic receptor|α1 adrenergic] and dopamine receptors. Little is known about the in vivo activity of Rugulovasine A and B, although they have hypotensive effects in cats.