Ravi Bhushan


Ravi Bhushan was a Professor of Chemistry at Indian Institute of Technology Roorkee who worked in the areas of natural products chemistry, protein chemistry, and chiral analysis by liquid chromatography.

Education and academic career

Bhushan began his education in his native India, completing his undergraduate and master's degrees from the University of Jodhpur. He received his Ph.D. in chemistry in 1978 at the University of Jodhpur. Bhushan joined as a lecturer at the University of Roorkee in 1979 and was later selected for the position of full professor of chemistry in 1996 and served there till retirement in 2018.

Research

He started his research in the chemistry of natural products. At Washington State University he established early steps in the metabolism of d-neomethyl-α-D-glucoside in pipermint rhizomes via in vivo studies. Bhushan developed a de novo method for direct resolution of certain racemates by liquid chromatography. Later, the approach was applied for direct enantioseparation of several active pharmaceutical ingredients. It is now an established approach in literature. 1994 onwards, the method was extended to such resolutions by ligand exchange principle. The method is of significant importance to pharmaceutical industry and analytical laboratories associated with regulatory agencies for determination and control of enantiomeric purity of a variety of APIs since many of them are marketed and administered as racemic mixture while only one enantiomer is therapeutically useful.
Bhushan supervised the Ph.D. theses of > 30 scholars and has published more than 270 research papers.

Editorial work

Bhushan is a member of editorial board of