Rapanone


Rapanone is an organic compound and natural product. It is a tridecyl side chain derivative of 2,5-dihydroxy-1,4-benzoquinone with the chemical formula C19H30O4.

Occurrence

It occurs in various plant species including Aconitum lamarckii, Aegiceras corniculatum, Embelia ribes, Heliotropium indicum, and several Ardisia species. It also occurs in fungi including Irpex lacteus.

Synthesis

Rapanone can be synthesized by the alkylation of 2,5-dihydroxy-1,4-benzoquinone with the peroxide of myristic acid.

Pharmacology

Rapanone derivatives and related quinonoids are being researched for their potential anticancer properties, although their mechanism is unclear. It is also classified as an antiparasitic agent. Some studies claim iron chelating and free radical scavenging properties in rapanone and its derivatives.

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