RTC
- Coronavirus
- Dirección General de Radio, Televisión y Cinematografía
- RCT (disambiguation)
- RTC (Cape Verde)
- RTC (record label)
- RTC (treaty)
- RTC Transit
- Radiotechnique
- Radiotelevisão Comercial
- Rail traffic controller
- Rails-to-Trails Conservancy
- Railway Technical Centre
- Rational Team Concert
- Real-time clock
- Real-time communication
- Real-time computing
- Recruit Training Command, Great Lakes, Illinois
- Redmond Town Center
- Reformed Theological College
- Regional Technical College
- Regional Transportation Commission of Southern Nevada
- Regional Transportation Commission of Washoe County
- Regional Trial Court
- Religious Technology Center
- Renton Technical College
- Residential treatment center
- Resolution Trust Corporation
- Reston Town Center
- Right to Censor
- Road traffic collision
- Rochester Telephone Company (disambiguation)
- Rochester Transit Corporation
- Rosette terminal complex
- Rotterdam Terror Corps
- Royal Thimphu College
- Réseau de transport de la Capitale
- Treaty of Chaguaramas