RIPOR2RHO family interacting cell polarization regulator 2 is a protein that in humans is encoded by the RIPOR2 gene.FunctionThe protein encoded by this gene stimulates the formation of a non-mitotic multinucleate syncytium from proliferative cytotrophoblasts during trophoblast differentiation. Alternative splicing of this gene results in multiple transcript variants. .Clinical significanceMutations in RIPOR2 are associated to hearing loss.