Protopanaxatriol
Protopanaxatriol is an organic compound that is an aglycone of ginsenosides, a group of steroid glycosides. It is a dammarane-type tetracyclic triterpene sapogenins found in ginseng and in notoginseng.
In rats, the oral bioavailability is about 3.7% and the half-life is 0.80 hours. PPT is unstable in acid, showing 40% degradation after 4 hours at 37°C both in pH 1.2 buffer solution and rat stomach contents. It is extensively metabolized in mice.