Progressive age-dependent DNA methylation changes start before adulthood in mouse tissues
Progressive age-dependent DNA methylation changes start before adulthood in mouse tissues is a scholarly work by Masaki Takasugi, published in 2010 in ''Mechanisms of Ageing and Development''. The main subjects of the publication include Differentially methylated regions, gene, Rett syndrome, epigenetics, biology, gene expression, methylation, Epigenetics of physical exercise, CpG site, genetics, and DNA methylation. These results suggest that the DNA methylation status consistently move toward development/maturation throughout lifespan, and the tissue-dependent epigenetic or transcriptional status underlies the methylation changes.