Pilosocereus tillianus has green to grayish green stems with 11–12 ribs. Its branches are more-or-less upright. The areoles have spines up to long. Flowering areoles have flexible spines and silky hairs up to long in dense tufts. Non-flowering areoles have rigid spines and fewer silky hairs. The flower is long with greenish outer segments and white inner tepals. The fruit is red.
Taxonomy
Pilosocereus tillianus was first described in 1982. The specific epithettillianus is assumed to refer to Hans Till, an Austriancactusspecialist. It has been sunk into P. lanuginosus, and also reduced to a subspecies of that species, P. lanuginosus subsp. tillianus. Its relatively short flowers and large number of flexible spines distinguish it from P. moritzianus which is also found in Venezuela, and which has also been treated as a subspecies of P. lanuginosus.