William Pierce
William Pierce may refer to:
Politics
- William Pierce (Georgia politician), Continental Congressman from Georgia
- William Pierce (Illinois politician), Illinois state representative
- William Luther Pierce, white nationalist and political activist
- Bud Pierce, politician in Oregon
Sports
- Billy Pierce, American baseball player
- Bill Pierce (baseball), Negro leagues baseball player and manager
Other
- William Pierce (serial killer), American serial killer also known as "Junior"
- William Henry Pierce (missionary), Canadian missionary for the Methodist church
- William H. Pierce, American mortuarist
- William S. Pierce, American surgeon and chemical engineer
- William Pierce (robber), perpetrator of the Great Gold Robbery