Pholedrine
Pholedrine, also known as 4-hydroxy-N-methylamphetamine and sold under the brand names Paredrinol, Pulsotyl, and Veritol among others, is a sympathomimetic drug used in topical eye drops to dilate the pupil. It can be used to diagnose Horner's syndrome.
In 2004, it remained marketed only in Germany.
Pharmacology
Pharmacodynamics
Pholedrine is described as a sympathomimetic, antihypotensive, and ephedrine-like agent.Chemistry
Pholedrine, also known as 4-hydroxy-N-methylamphetamine, is a substituted phenethylamine and amphetamine derivative. It is structurally related to methamphetamine, norpholedrine, oxilofrine, and tyramine.It is used pharmaceutically as the sulfate salt.
The predicted log P of pholedrine ranges from 1.12 to 1.7.