Phenescaline
Phenescaline, or 3,5-dimethoxy-4-phenylethoxyphenethylamine, is a lesser-known drug of the phenethylamine and scaline families It is an analogue of mescaline. Alexander Shulgin first synthesized phenescaline. In his book PiHKAL , the minimum dose is listed as 150 mg, and the duration is unknown. Phenescaline produces a threshold effect. Very little data exists about the pharmacological properties, metabolism, and toxicity of phenescaline. The drug is an antagonist of the serotonin 5-HT2A receptor, with an affinity of 59nM.