Peptoniphilus


Peptoniphilus is a genus of bacteria in the phylum Bacillota.

Etymology

The name Peptoniphilus derives from:Neo-Latin noun peptonum, peptone; Neo-Latin adjective philus from Greek adjective philos meaning friend, loving; Neo-Latin masculine gender noun Peptoniphilus, friend of peptone, referring to the use of peptone as a major energy source.

Classification

Peptoniphilus are gram positive anaerobic cocci that were formerly classified in the genus Peptostreptococcus. They are non-saccharolytic, use peptone as a major energy source and produce butyrate.

Clinical relevance

This genus is part of the vaginal and gut microbiota. They have been reported to as present in diabetic skin and soft tissue infections, bone and joint infections, surgical site infections, chorioamnionitis and bloodstream infections. They are typically found as part of polymicrobial infections but are difficult to recover with usual clinical cultures. They have been increasingly reported with the more widespread use of 16S PCR and MALDI-TOF for identification. They are noted to be linked with an impairment of wound-healing in patients with diabetic foot ulcers if present in abundance during the initial infection.

Phylogeny

The currently accepted taxonomy is based on the List of Prokaryotic names with Standing in Nomenclature and National Center for Biotechnology Information
Species incertae sedis:
  • "P. duodeni" Maihe et al. 2017
  • "P. genitalis" Abou Chacra et al. 2024
  • "P. hominis" Hitch et al. 2024 non Huang et al. 2024
  • "P. hominis" Huang et al. 2024 non Hitch et al. 2024P. ivorii
  • "Ca. P. massiliensis" Fenollar et al. 2006P. olsenii Song, Liu & Finegold 2010
  • "P. phoceensis" Mourembou et al. 2016
  • "P. nemausus" Enault et al. 2019
  • "P. septimus" Wang et al. 2022
  • ''P. urinimassiliensis''