Panther Creek
- East Bay River
- Jim Edgar Panther Creek State Fish and Wildlife Area
- Navarre, Florida
- North Fork Embarras River
- Panther Branch (disambiguation)
- Panther Creek (Blackwater River)
- Panther Creek (Brush Creek tributary)
- Panther Creek (Caldwell County)
- Panther Creek (Cape Girardeau County)
- Panther Creek (East Fork Grand River tributary)
- Panther Creek (Florida)
- Panther Creek (James River)
- Panther Creek (Little Schuylkill River)
- Panther Creek (Mackinaw River)
- Panther Creek (Osage Fork Gasconade River)
- Panther Creek (Osage River)
- Panther Creek (Schoharie Creek tributary)
- Panther Creek (Spring Brook)
- Panther Creek (Tug Fork)
- Panther Creek (Wind River)
- Panther Creek Consolidated Independent School District
- Panther Creek Falls
- Panther Creek High School (North Carolina)
- Panther Creek High School (Valera, Texas)
- Panther Creek State Park
- Panther Creek Township, Cass County, Illinois
- Panther Creek Valley
- Panther Creek Wind Farm
- Panther Run
- Raccoon River
- Salmon River (Idaho)