The Pamplona Colonial House Museum is a museum located in northeastern Colombia. It is one of the oldest museums in the department of [Norte de Santander Department|Santander Department|Norte de Santander].
The museum has in its possession collections of historical objects. The museum contains pre-Columbian pottery and artifacts from indigenous groups of Norte de Santander such as the U'wa and Barí people. The museum also has a mummy and bones as well as objects of the Chitarero culture. The museum also contains sacred art from colonial times. The museum contains exhibits about the Independence of Colombia as well as information about the early days of the establishment of the republic. The museum contains fragments of the Bolivar plane that crashed in Pamplona, as well as typewriters, oil paintings, coins and medals. The museum also exhibits photographs of the Thousand Days' War.