Poliovirus receptor-related 3


Poliovirus receptor-related 3, also known as nectin-3 and CD113, is a human protein of the immunoglobulin superfamily which forms part of adherens junctions.

Function

s are immunoglobulin-like adhesion molecules that interact with afadin. Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin -catenin system in epithelial cells.

Interactions

PVRL3 has been shown to interact with: