PSC
- Centre démocrate humaniste
- Christian Social Party (Belgium)
- Christian Social Party (Belgium, defunct)
- Extractivism
- Judge
- PSC (musical group)
- Pacific Salmon Commission
- Pacific Science Center
- Palestine Solidarity Campaign
- Palestinian Satellite Channel
- Palm Springs, California
- Pan-Atlantic Steamship Company
- Pancreatic stellate cell
- Parkdale Secondary College
- Parkwood Secondary College
- Partido Social Conservador
- Partido Social Cristiano (disambiguation)
- Partido Socialista de Chile
- Partille Sport Club
- Peace and Security Council
- Pediatric Symptom Checklist
- Peirce Smith converter
- Pensacola State College
- People with Significant Control
- Permanent split capacitor
- Personal service corporation
- Personal supercomputer
- Peru State College
- Peter Symonds College
- Philippine Science Consortium
- Philippine Sports Commission
- Photography Studies College
- Phylogenetic species concept
- Pisces (constellation)
- Pittsburgh Supercomputing Center
- PlayStation Classic
- Pluripotent stem cell
- Pointe-Saint-Charles
- Polar Security Cutter program
- Polar stratospheric cloud
- Politburo Standing Committee of the Chinese Communist Party
- Political and Security Committee
- Polk State College
- Polymer solar cell
- Porsche Supercup
- Port State Control
- Postsynaptic current
- Power supply
- Premature stop codon
- Prescot railway station
- Prestressed concrete
- Primary sclerosing cholangitis
- Printer-Scanner-Copier
- Private security contractor
- Production sharing contract
- Proportionality for Solid Coalitions
- Protein Sciences
- Public Safety Canada
- Public Service Commission (disambiguation)
- Public Service of Canada
- Putonghua Proficiency Test
- Social Christian Party (Brazil)
- Socialists' Party of Catalonia
- Tri-Cities Airport (Washington)