4-Hydroxybenzaldehyde


4Hydroxy­benzaldehyde is an organic compound with the formula. Along with 2-hydroxybenzaldehyde and 3-hydroxybenzaldehyde, it is one of the three isomers of hydroxybenzaldehyde.

Synthesis, reactions, uses

4-Hydroxybenzaldehyde is prepared by reaction of phenol with chloroform, which gives isomeric hydroxybenzal chlorides. Hydrolysis of the C-Cl bonds gives the aldehyde.
4-Hydroxybenzaldehyde is a precursor to 4-hydroxyphenylglycine, which is itself a precursor to penicillins. In the Dakin oxidation, 4-hydroxybenzaldehyde reacts with hydrogen peroxide in base to form hydroquinone.

Metabolism and occurrence

is an enzyme found in carrots.
4-Hydroxybenzaldehyde is found in the orchids Gastrodia elata, Galeola faberi, and the Vanilla orchids.

Cited sources

Category:4-Hydroxyphenyl compounds
Category:4-Hydroxybenzaldehyde derivatives