Oxbow virusOxbow virus '' is a single-stranded, enveloped, negative-sense RNA orthohantavirus.Natural reservoirOxbow virus was isolated from an American shrew mole, captured in Gresham, Oregon, in September 2003.VirologyThe genome of the Oxbow virus along the full length of the S, M, and partial L-segment nucleotide and amino acid sequences show a low sequence similarity to rodent-borne hantaviruses. Phylogenetic analysis demonstrated that Oxbow virus and Asama virus are related to soricine shrew-borne hantaviruses found in North America, Europe, and Asia. This suggests both these viruses evolved with cross-species transmission.