Orson
- Ben Mendelsohn
- Doctor Who
- Kyle MacLachlan
- Orso (disambiguation)
- Orson (band)
- Orson Bean
- Orson F. Whitney
- Orson Flagg Bullard
- Orson Hodge
- Orson Hyde
- Orson Krennic
- Orson Pratt
- Orson Pratt Huish
- Orson Scott Card
- Orson Spencer
- Orson Squire Fowler
- Orson Welles
- Orson, Iowa
- Orson, Pennsylvania
- Pac-Man World
- Samuel Anderson (actor)
- The Ice Age Adventures of Buck Wild
- The Middle (TV series)
- Tweety Bird
- U.S. Acres
- Utkarsh Ambudkar
- Valentine and Orson