Optogenetic Control of Neural Circuits in the Mongolian Gerbil
Optogenetic Control of Neural Circuits in the Mongolian Gerbil is a scholarly work by Benedikt Grothe, Stylianos Michalakis, and Martin Biel, published in 2018 in ''Frontiers in Cellular Neuroscience''. The main subjects of the publication include computer science, biological neural network, biology, brain implant, neuroscience, synaptic plasticity, optogenetics, and Meriones unguiculatus. The authors demonstrate a reliable gene delivery system using an AAV8(Y337F)-pseudotyped recombinant adeno-associated virus (AAV) 2-based vector in which the pan-neural human synapsin (hSyn) promoter drives neuron-specific expression of CatCH (Ca2+-permeable channelrhodopsin) or NpHR3.0 (Natronomonas pharaonis halorhodopsin).