Oplurus quadrimaculatus can reach a length of. This iguana is greyish, with a spotted back and tail and legs covered with enlarged, spinous scales. It spends hours basking in sunlight. It is mainly insectivorous. Mating lasts just a few seconds and the eggs are laid in sheltered areas.
Madagascar spotted spiny-tailed iguana lives on loamyslopes, clay expanses and large rocks in various environment, from the arid regions in dry spiny forests to northern wetlands and humid areas close to the rainforest and in shrubland.