Ohio State Route 278
State Route 278 is a north-south state highway located in the southeastern part of the U.S. state of Ohio. The southern terminus of SR 278 is at U.S. [Route 50 in Ohio|US 50] approximately east of McArthur. The highway's northern terminus is at the T-intersection it has with Ohio [State Route 595|SR 595] nearly northwest of Nelsonville.
Established in the early 1930s, SR 278 primarily connects rural communities in Vinton, Hocking, and Athens Counties. In Vinton County, it passes through and provides access to the Zaleski State Forest and Lake Hope State Park.