OFC
- Conduit and sink OFCs
- Corporate Office Properties Trust
- Daihatsu OFC-1
- Kickers Offenbach
- OFC Oostzaan
- Oceania Football Confederation
- Odisha FC
- Officer railway station
- Offshore financial centre
- Online Film Critics Society
- Open Financial Connectivity
- Open fiber control
- Open-face Chinese poker
- Optional federal charter
- Orbitofrontal cortex
- Order from Chaos
- Orpington F.C.
- Osteitis fibrosa cystica
- Ottawa Folklore Centre
- Oxy-fuel welding and cutting
- Oxygen-free copper
- SMS language