Acetanisole

Acetanisole is an organic compound with the formula. It can be viewed as derivative of acetophenone and of anisole. It has an aroma described as sweet, fruity, nutty, and similar to vanilla. In addition the odor of acetanisole is sometimes described as butter-like or caramel-like. It is used commercially in some soap fragrances. It is a component of anise oil.

Preparation

Acetanisole can be prepared synthetically by Friedel-Crafts acylation of anisole with acetyl chloride:

Reactions

4-Methoxyacetophenone is a standard substrate or product of much research, such as transfer hydrogenation and directed arylations.