Niranjan Parajuli


Niranjan Parajuli is a Nepali chemist, biochemist, and biotechnologist. He served as President of the Nepal Chemical Society from 2019 to 2021, and was a Professor of Chemistry at Tribhuvan University. His research focuses on microbial biotechnology, natural products, protein engineering and computational chemistry.

Research

Parajuli’s research focuses on microbial biotechnology, natural product discovery, protein engineering, and computational chemistry. His work includes genome mining, metabolomics and in silico studies of bioactive compounds. He has published studies on antibiotic biosynthesis, secondary metabolites from plants and microorganisms, and therapeutic compound modeling.

Awards and recognition

Personal life

Parajuli is married to journalist Madhabi Bhatta and has two sons.

Selected publications

  1. Park, J.W., Hong, J.S.J., Parajuli, N., et al. “Genetic dissection of the biosynthetic route to gentamicin A2 by heterologous expression of its minimal gene set.” Proceedings of the National Academy of Sciences, 105, 8399–8404.
  2. Parajuli, N., Williams, G.J. “A high-throughput screen for directed evolution of aminocoumarin amide synthetases.” Analytical Biochemistry, 419, 61–66.
  3. Upadhyaya, S.R., Bashyal, J., Raut, B.K., Parajuli, N. “In silico study of therapeutic potential of natural polyphenol derivatives targeting pancreatic lipase.” Discover Chemistry, 2, 189.
  4. Joshi, S., Huo, C., Budhathoki, R., Gurung, A., Bhattarai, S., Sharma, K.R., Kim, K.H., Parajuli, N. “HPLC-ESI-HRMS/MS-Based Metabolite Profiling and Bioactivity Assessment of Catharanthus roseus.” Plants, 14, 2395.
#