NifurzideNifurzide is a nitrofuran derivative and intestinal anti-infectious agent active against Escherichia coli.SynthesisEsterification of 5-nitrothiophene-2-carboxylic acid with ethanol gives the ester. Treatment with hydrazine forms its hydrazide. Nifurzide is the hydrazone formed between and 5-nitrofuran-2-acrylaldehyde.