Until 2012, the northernmost portion of this route traversed Old Coors Road between Coors Boulevard and Central Avenue. NM 45 has since been realigned to Coors Boulevard and Coors By-Pass and extended north of Central Avenue, replacing the portion of NM 448 between St. Joseph's Drive and Coors By-Pass, and turning over Old Coors Road to local control to be realigned with Yucca Drive.