N-Desethylprotonitazene
N-Desethylprotonitazene is a benzimidazole opioid with potent analgesic effects which has been sold as a designer drug. It was first identified in 2024 as an active metabolite of the closely related compound protonitazene, and was found to have less potency than it while still being more potent than fentanyl.
It was discovered in a drug sample from Chicago in June 2025.