Muscavirus


Muscavirus is a genus of viruses, in the family Hytrosaviridae. The fly Musca domestica is the natural host. There is only one species in this genus: Musca domestica salivary gland hypertrophy virus. Diseases associated with this genus include: salivary gland hypertrophy, and complete sterility of infected female flies by inhibiting eggs development.

Structure

Viruses in the genus Muscavirus are enveloped, with rod-shaped geometries. The diameter is around 50 nm. Genomes are circular, around 124kb in length. The genome has 108 open reading frames.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
MuscavirusRod-shapedEnvelopedCircularMonopartite

Life cycle

Viral replication is nuclear. DNA-templated transcription is the method of transcription. Musca domestica serve as the natural host. Transmission routes are parental and contamination.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
MuscavirusInsects: house fliesEpithelium: secretory salivary glands; ovarioles; gonadsContact: food; horizontal; verticalBudding; horizontal; verticalNucleusNucleusContact: food; horizontal; vertical