He began his career with small roles in television shows. Goud’s first breakthrough role in film came through with DJ Tillu. He went on to reprise his role in its Tillu Square as well. Speaking about his role as Tillu’s father, AbhilashaCherukuri of The New Indian Express wrote that Goud emerged in "steady form without missing a single beat." Jeevi of Idlebrain.com wrote that Goud is naturally talented and praised his comic timing. Speaking about his role in Mad, Sangeetha Devi Dundoo of The Hindu stated that, "Muralidhar is easilyone of the best actors in Telugu cinema today to play the frustrated father who delivers snarky lines with a deadpan expression."