Multiple sclerosis functional composite
The Multiple Sclerosis Functional Composite is a clinical trial outcome measure of assessing the severity of multiple sclerosis primarily used in research. The score is based on a combination of timed tests of walking, arm function, and cognitive ability. It was developed over two years from 1994 to 1996 by the National [Multiple Sclerosis Society].
MSFC was developed to improve the standard measure of MS disability for clinical trials and to create a multidimensional metric of overall MS clinical status. The evaluation includes a three-part performance scale:
- Timed 25-Foot Walk - assessment of leg function by moving a short walking distance
- 9-Hole Peg Test - assessment of arm function using breadboard test
- Paced Auditory Serial Addition test - attention/concentration test to assess cognitive functions