Miyaura borylation
Miyaura borylation, also known as the Miyaura borylation reaction, is a named reaction in organic chemistry that allows for the generation of boronates from vinyl or aryl halides with the cross-coupling of bisdiboron in basic conditions with a catalyst such as PdCl2. The resulting borylated products can be used as coupling partners for the Suzuki reaction.
Scope
The Miyaura borylation has shown to work for:Alkyl halides, aryl halides, aryl halides using tetrahydroxydiboron, aryl halides using bis-boronic acid, aryl triflates, aryl mesylates, vinyl halides, vinyl halides of α,β-unsaturated carbonyl compounds, and vinyl triflates.