Mirogabalin
Mirogabalin is a gabapentinoid medication developed by Daiichi Sankyo. Gabapentin and pregabalin are also members of this class. As a gabapentinoid, mirogabalin binds to the α2δ subunit of voltage-gated calcium channel, but with significantly higher potency than pregabalin. It has shown promising results in Phase II clinical trials for the treatment of diabetic peripheral neuropathic pain.
Phase III trial results:
- Effective: for post-herpetic neuralgia
- Ineffective: for fibromyalgia
- Effective: for diabetic peripheral neuropathic pain