Mir-615 microRNA precursor family

mir-615 microRNA is a short non-coding RNA molecule belonging both to the family of microRNAs and to that of small interfering RNAs. MicroRNAs function to regulate the expression levels of other genes by several mechanisms, whilst siRNAs are involved primarily with the RNA interference pathway. siRNAs have been linked through some members to the regulation of cancer cell growth, specifically in prostate adenocarcinoma.

miR-615 and NGX6

Nasopharyngeal carcinoma-associated gene 6 acts as a tumour suppressor gene in colon cancer. miR-615 has been found to be downregulated in NGX6-transfected cells, although identification of its target genes has not yet been achieved.

''Hox'' cluster conservation

miR-615 has been found to reside within Hox gene clusters, alongside Hox genes other miRNAs. Hox genes are involved in anterior-posterior axis patterning. miR-615 is located at the HOXC5 intron in mammals.