Mike, MissouriMike is an unincorporated community in Chariton County, in the U.S. state of Missouri.The community is on Missouri Route 5 approximately midway between Keytesville to the south and Marceline in adjacent Linn County to the north.HistoryA post office called Mike was established in 1890, and remained in operation until 1906. The community most likely has the name of a resident.