Mesitol


Mesitol is an organic compound with the formula 3C6H2OH. It is one of several isomers of trimethylphenol. The name and structure of mesitol derives from the combination of mesitylene and phenol.

Synthesis

Mesitol is the main product from the methylation of phenol with methanol in the presence of a solid acid.
It can also be obtained by reaction of mesitylene with peroxymonophosphoric acid:
An alternative route involves palladium-catalyzed reaction of bromomesitylene with potassium hydroxide.