Megrivirus


Megrivirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Birds serve as natural hosts. There are five species in this genus. Diseases associated with this genus include: hepatitis.

Taxonomy

The genus contains the following species, listed by scientific name and followed by the exemplar virus of the species:Megrivirus aturhepa; Megrivirus A2, also called Duck megrivirusMegrivirus berockdo; Megrivirus B1, also called Pigeon mesivirus 1Megrivirus chigalli; Megrivirus C1, also called Chicken megrivirusMegrivirus deharri; Megrivirus D1, also called Harrier megrivirusMegrivirus epengu; Megrivirus E1, also called Penguin megrivirus

Structure

Viruses in Megrivirus are non-enveloped, with icosahedral and spherical geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 9kb in length.
GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
MegrivirusIcosahedralPseudo T=3Non-envelopedLinearMonopartite

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. The virus exits the host cell by lysis, and viroporins. Birds serve as the natural host.
GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
MegrivirusUnknown-Cell receptor endocytosisLysisCytoplasmCytoplasmUnknown