Mechanical index
Mechanical index is a unitless ultrasound metric originally developed by Robert Apfel and Christy Holland. It is defined as
where
MI is measured with a calibrated hydrophone in a tank of degassed water. The pulse pressure amplitudes are measured along the central axis of the ultrasound beam. The Pr is calculated by reducing it using an attenuation coefficient of 0.3 dB/cm/MHz.
MI is a unitless number that can be used as an index of cavitation bio-effects; a higher MI value indicates greater exposure. Levels below 0.3 are generally considered to have no detectable effects. Currently the Food and [Drug Administration|FDA] stipulates that diagnostic ultrasound scanners cleared using the Federal Food, Drug, and [Cosmetic Act#Premarket_notification_(510(k),_PMN)|510(k)] pathway
cannot exceed a mechanical index of 1.9.