List of mayors of Perryville, Missouri
The city of Perryville, Missouri, which is located in Missouri's 8th congressional district in southeastern Missouri, is the county seat and the largest city of Perry County, Missouri. The city was incorporated in 1831.
List of Mayors
Perryville mayors since 1882.| Mayor | Took office | Left office | Additional information |
| Charles A. Weber | 1880 | 1896 | Druggist and apothecary, founder of a general store, county clerk. In 1861, he raised a company for the Missouri Militia and served as its captain. In 1862, he organized the 64th regiment of the Missouri Militia and was commissioned a major. In 1864, he was commissioned a lieutenant colonel of the 64th regiment. In 1889, he was elected a probate judge. Judge Weber was born in Planena in the Kingdom of Prussia. His wife was also a native of the Kingdom of Hanover. |
| Robert M. Wilson | 1896 | 1900 | |
| Charles Edward Kiefner | 1900 | c. 1903 | U.S. Representative, 1925–1927; 1929–1931 |
| Thomas E. Hudson | 1904 | 1908 | |
| Henry Francis Weiss | 1908 | 1918 | He died in Cape Girardeau, Missouri. His parents were born in Germany in the 1840s. |
| Dr. Louis W. Holtmann | c. 1918 | 1918 | Dentist. He died of pneumonia and influenza in Perryville in 1918 at the age of 33. |
| Henry F. Weiss | 1919 | 1922 | |
| Leo A. Herbst | 1922 | c. 1923-1924 | |
| Phillip Louis Zoellner | 1923 | 1932 | |
| John Kiefner | 1932 | 1942 | |
| John Francis Lottes, Jr. | 1942 | 1948 | |
| Edwin J. Layton | 1948 | 1950 | |
| Clarence J. Hinni | 1950 | 1951 | |
| John Francis Lottes, Jr. | 1951 | 1952 | |
| Clarence J. Hinni | 1952 | 1954 | |
| Wallace Young | 1954 | 1956 | |
| Austin G. Harter | 1956 | 1960 | In 1964, he retired from the U.S. Army Reserve after 33 years. |
| Carl O. Peterson | 1960 | 1964 | Born in Renville, Minnesota. Former owner of the Perryville Cheese Company |
| Wallace Gagnepain | 1964 | 1972 | |
| Paul L. Gibbar | 1972 | 1978 | |
| Frank W. "Bill" Bergman | 1978 | 1980 | |
| Larry H. Pryor | 1980 | 1982 | He was the owner and operator of the Park-Et Motel. He died in 1993 at Barnes Hospital in St. Louis at age 54. |
| Kim R. Moore | 1982 | 1984 | |
| Robert J. Miget | 1984 | 2007 | U.S. Army veteran who was employed at the Republic-Monitor newspaper, 1959–2001. |
| Debbie Gahan | 2008 | Perryville's first woman mayor. | |
| Ken Baer | Former Navy Civil Engineer Corp Officer |