May 22 (Eastern Orthodox liturgics)

Feasts

• '''Commemoration of the Holy Fathers of the Second Ecumenical Council'''

Saints

• Righteous Melchizedek, King of Salem
• Martyr Sophia the Healer.
• Martyr Marcellus, by being placed in molten lead.
• Martyr Codratus, by being dragged by horses.
• Martyr Basiliscus of Comana with Eutropius and Cleonicus
• Saint Donatus of Thmuis, Bishop and Martyr
• Saint John Vladimir, King of Serbia, Martyr, Wonderworker

Pre-Schism Western saints

• Saint Ausonius, first Bishop of Angoulême
• Saint Marcian of Ravenna, Bishop and Confessor
• Martyrs Castus and Emilius, by fire, in Carthage
• Martyrs Timothy, Faustinus and Venustus, in Rome, under Julian the Apostate
• Saint Helen of Carnarvon, Princess, a late 4th-century founder of churches in Wales, and wife of Emperor Magnus Clemens Maximus
• Saint Helen of Auxerre
• Saint Julia of Corsica the martyr, who was crucified
• Saint Quiteria the virgin-martyr, in Spain
• Saint Romanus of Subiaco, ascetic who ministered to Saint Benedict of Nursia
• Saint Fulk
• Saint Boethian of Pierrepont, Irish, Benedictine monk, martyred in France
• Saint Conall, of Inniskeel, County Donegal, Abbot of the island monastery of Inniskeel, where there is a holy well dedicated to him
• Saint John of Parma, abbot of Saint John's at Parma from 973 to c. 982, then under Cluniac observance
• Saint Bobo, hermit

Post-Schism Orthodox saints

• Saint Kali of Asia Minor
• New Hieromartyr Zachariah of Prussa
• Blessed James, youth, of Borovichi, Wonderworker
• New Martyr Demetrios of Peloponnesos
• Venerable Monk-martyr Paul of Mt. Athos, at Tripolis, Peloponnesus

New martyrs and confessors

• New Hieromartyr Michael Borisov, priest

Other commemorations

• Synaxis of the Cyprus Icon of the Most Holy Mother of God.
• Repose of Cleopas of Valaam, disciple of Saint Paisius Velichkovsky
• Repose of Eldress Macrina of Volos