Mark Stradiotto
Mark Stradiotto is a Canadian chemist. He is currently the Arthur B. McDonald Research Chair and the Alexander McLeod Professor of Chemistry in the Department of Chemistry at Dalhousie University.
Education and academic career
Stradiotto received his BSc in applied chemistry and PhD in organometallic chemistry from McMaster University, the latter under the supervision of Michael A. Brook and Michael J. McGlinchey. After conducting research as an NSERC Postdoctoral Fellow at the University of California at Berkeley with T. Don Tilley, Stradiotto moved to the Department of Chemistry at Dalhousie University where he now holds the rank of Professor with tenure. In July 2013, Stradiotto was named the Alexander McLeod Professor of Chemistry, and in 2020 he was named an Arthur B. McDonald Research Chair. In 2023 he received the Governor General of Canada Award for Innovation, and in 2024 was named a Fellow of the Royal Society of Canada.Research contributions
Stradiotto's research is directed toward developing new classes of ancillary ligands/transition metal complexes that exhibit interesting and unusual reactivity patterns, with the goal of incorporating such reactivity into synthetically useful catalytic substrate transformations that can be employed by end-users in both academic and industrial settings. In particular, he is best known for developing the "DalPhos" ligand family and derived catalyst systems for palladium and nickel cross-couplings that are of relevance to the pharmaceutical industry, many of which have been commercialized. Reported DalPhos ligands and their substrate applications include:- Ni/CgPhen-DalPhos
- Ni/PhPAd-DalPhos
- Ni/Phen-DalPhos
- Ni/PAd2-DalPhos
- Ni/NHP-DalPhos
- Ni/CyPAd-DalPhos
- Ni/PAd-DalPhos
- Pd/Mor-DalPhos
Major publications
- "The development of cage phosphine 'DalPhos' ligands to enable nickel-catalyzed cross-couplings of aryl electrophiles" K. M. Morrison and Mark Stradiotto*.
- "Ligand Design in Metal Chemistry: Reactivity and Catalysis." Edited by Mark Stradiotto and Rylan J. Lundgren Wiley, 2016. - .
- C. M. Lavoie, P. M. MacQueen, N. L. Rotta-Loria, R. S. Sawatzky, A. Borzenko, A. J. Chisholm, B. K. V. Hargreaves, R. McDonald, M. J. Ferguson and Mark Stradiotto*.
- R. J. Lundgren, B. D. Peters, P. G. Alsabeh, and Mark Stradiotto*.
- K. D. Hesp and Mark Stradiotto*.
- R. J. Lundgren and Mark Stradiotto*.
- R. J. Lundgren, A. Sappong-Kumankumah, and Mark Stradiotto*..
- K. D. Hesp and Mark Stradiotto*.